What does this medicine do and what is it used for?
Summary Dormicum 15 mg
Dormicum 15 mg The active substance in Dormicum 15 mg is midazolam. Midazolam is one of the benzodiazepines. It has a calming effect, relaxes muscles, reduces feelings of anxiety and affects the transmission of electrical stimuli in the brain. Doctors prescribe it for insomnia, agitation, seizures of epilepsy, hiccups and alcohol withdrawal. Insomnia Symptoms Insomnia is referred to when someone has been sleeping poorly for some time and therefore does not function properly during the day. Sleeping problems often arise from stress or worry. But physical complaints such as pain or itching can also cause insomnia. TherapyIf you come to your doctor with sleep problems, the doctor will usually not prescribe a sedative right away. The doctor will first try to remedy the cause of the sleep complaints. For example with a painkiller if you suffer from pain. Or with soothing advice if you stay awake mainly due to worrying. Some of these advices are.
- Exercise during the day or early in the evening.
- Do something relaxing an hour before going to sleep.
- Don’t take naps during the day.
- Keep a steady rhythm during the time you go to bed and get up.
- Do not have coffee in the evening.
- Do not take alcohol to sleep.
- Do not take solid food 2-3 hours before going to bed.
- Provide a quiet, cool bedroom and a nice bed.
- Do not use the bedroom as a work, study or TV room.
- If you can’t sleep, get up and do something else in another room. Do not go back to bed until you are tired.
If these measures do not help or are not possible, the doctor may prescribe this medicine for a few days. Effect Dormicum 15 mg (Midazolam) has a muscle relaxant, calming effect and makes drowsy. It thus promotes that you fall asleep. This medicine is especially suitable if you have difficulty falling asleep. So not if you expect to wake up often during the night. Effect Usually within half an hour after taking it you will become sleepy and calm. Therefore, make sure that you are at home, do not have to do complicated jobs and can easily reach your bed. The effect usually lasts for two to four hours. This sleeping aid only works well if you use it occasionally. For example every three days. With daily use, the effect diminishes because your body gets used to the effect.Use in seriously ill people Dormicum 15 mg is also used in people who are seriously ill or dying. It is given when they are very anxious, agitated, confused or in a lot of pain.
They are artificially kept asleep by this drug. Due to the short duration of action of this drug, it is also possible to wake up quickly in the meantime. It is also possible that people sleep all night and are awake for a few hours during the day. This drug is then usually administered via an IV or injection. Restlessness During examinations or minor proceduresMedical examinations or minor medical procedures can sometimes be so unpleasant that it makes you very restless. This makes the procedure more difficult and increases pain and discomfort. This medicine allows you to undergo an examination or procedure more relaxed. This drug also has a muscle relaxant effect, which is an additional advantage for certain procedures. For example, if a tube has to be inserted during an endoscopy. The tablet works within half an hour. The injection works within ten minutes. The effect usually lasts for two to four hours. In case of severe agitation or restlessnessThis medicine is sometimes given when you are very agitated or restless. This can be so serious that you and are a danger to yourself and the environment. The counselor will first try to calm you down. If this fails, the care provider can give you a calming agent such as Dormicum 15 mg.
This drug is then administered by injection. The injection works within ten minutes. Epilepsy Symptoms Epilepsy (epilepsy) is a disorder of the brain in which a kind of short circuit occurs in the brain. This happens in attacks. The brain is disrupted for a moment, for example, resulting in muscle twitching or unconsciousness. Cause Epilepsy can have all kinds of causes, for example a lack of oxygen during birth, meningitis, an accident, a stroke and (rarely) a brain tumor. However, the cause is usually unknown and there is a predisposition. The disease can develop at any age but usually starts in childhood. TherapyIf your seizure lasts longer than five minutes, it must be stopped quickly. Usually this is done with an enema containing diazepam. Sometimes midazolam is used. Midazolam can then be administered by people close to you. Midazolam can be administered as a nasal spray, as an injection, or as an enema. It can also be administered through the cheek pouch. Midazolam is then absorbed into the blood through the cheek pouch.
Dormicum 15 mg is sometimes used in newborn children with seizures. The doctor often starts with phenobarbital. If phenobarbital doesn’t work, the doctor can use midazolam. Effect Midazolam affects stimuli in the brain that can trigger epileptic seizures. Midazolam as an enema works within 10 to 20 minutes. Midazolam as an injection works within minutes. The effect lasts for 2 to 4 hours. Constant hiccups CauseWith hiccups, the diaphragm (a muscle between the stomach and lungs) contracts by itself. It can be caused by eating or drinking too quickly, not chewing properly or by carbonated drinks. Alcohol can also cause hiccups. The nerves in the throat and diaphragm are stimulated by this and the diaphragm starts to contract (cramps). Sometimes people with a disease of the lung membranes or stomach often have hiccups. Usually the hiccups are harmless, it generally disappears after a short time. Occasionally, however, the hiccups last for several days or longer. This can lead to chest pain and exhaustion. TherapyEating and drinking slowly is the best way to prevent hiccups. Baclofen is sometimes given for prolonged hiccups. If this does not work, or is not possible, Dormicum 15 mg can be given. It is not known how this medicine works for hiccups. Alcohol Withdrawal Symptoms If you are addicted to alcohol and want to stop, you may experience withdrawal symptoms such as excessive sweating, nausea, headache, irritability, anxiety, increased heart rate, tremors, insomnia, hallucinations and seizures. Treatment Midazolam is used to reduce these withdrawal symptoms for the first few days after stopping. OperationDormicum 15 mg has a calming effect, relaxes muscles, reduces anxiety and can prevent epileptic seizures. This reduces withdrawal symptoms such as anxiety, panic, tremors, increased heart rate, sweating and insomnia. You also reduce the risk of an epileptic seizure. The effect starts within half an hour after administration and lasts for 2 to 4 hours.
Side effects Dormicum 15 mg
What side-effects should I pay attention to? In addition to the desired effect, this medicine can cause side effects, also the next day. The main side effects are the following. Regularly, rarely the next day
- Drowsiness, drowsiness and fatigue. This reduces your ability to react and concentrate, which increases the risk of accidents. For example, you are more likely to fall if you have to get out of bed at night to go to the toilet. Accidents can also occur, for example: in traffic, when climbing a ladder, operating devices or during surveillance and control activities.
Regularly, after using the nasal spray
- Stinging or stinging sensation in the nose immediately after administration. Furthermore, a runny nose or sometimes pain in the nose.
- Irritation of the eyes and watery eyes immediately after application. These side effects are transient. If they persist, see your doctor.
- Irritation in the throat.
Sometimes, rarely even the next afternoon when used as a sleep aid
- Impaired coordination. This may make you clumsy in your movements and have difficulty speaking (articulating) clearly.
- Muscle weakness, feeling of weakness in muscles. This side effect can cause the following other complaints.
- Blurred or double vision due to a temporary effect on the eye muscles.
- Urinary incontinence or difficulty in passing urine. These side effects are caused by insufficient control of the bladder muscle.
- Snoring due to the weakening of the uvula. During your sleep, have you ever had problems with your breath stopping for a short time (sleep apnea)? You may be more affected by this medicine. Contact your doctor if you notice this.
- Fall, mainly because this drug also decreases coordination. Especially the elderly and people with muscle diseases have a chance of this.
- People with myasthenia gravis (a serious muscle disease) may be more prone to this disease. Consult your doctor if symptoms get worse (such as general muscle weakness, double vision, closing eyelids, difficulty swallowing, chewing or breathing).
- Slower thinking, memory problems, difficulty concentrating, less alert, confusion. These complaints may increase if you use this medicine for a longer period of time.
- Decrease feelings: this drug not only flattens emotions such as fear and tension, but also positive ones, such as happiness and satisfaction. Your involvement and empathy for others can also diminish.
- Gastrointestinal disorders, such as nausea, constipation and diarrhea, dry mouth or extra saliva, and problems swallowing. Changed appetite: more or less appetite. This also changes body weight.
- Headache and dizziness. These side effects usually go away after some time as you get used to the drug.
- Memory loss of events that occur while you are taking this drug. For example, events at night or just after administration.
- Sweating and palpitations.
- Dry eyes. Especially people with contact lenses can suffer from dry eyes.
- Rash and itching. Usually this is harmless, but (very rarely) the symptoms can be serious. If the rash looks unusual, if it affects you, or if you also develop a fever or blisters, see your doctor.
- Dependency. You may experience withdrawal symptoms if you stop taking it. The chance of this is very small with short-term use. Therefore, always taper off gradually if you have used this medication for several days in a row.
- Reduced effectiveness if you use this medicine every day for more than two weeks. The medicine then no longer works or works less well for sleeping. Therefore, use this medication only occasionally or for periods of up to two weeks.
- Nightmares, usually in the early morning.
- Unrest and irritability. So opposite symptoms than you would expect from this drug. Delusions and hallucinations can also occur. Children and the elderly are especially susceptible to these side effects. Consult the doctor in case of these symptoms. A lower dose or a different drug may be needed.
- Depressed feelings can be revealed.
- Less sex drive.
- With the injections: breathing problems. The doctor will pay attention to this during the treatment.
Consult your doctor if you experience too much of any of the above side effects or if you experience any other side effects that you are concerned about. How? Tablets
- Swallow the tablets with a glass of water.
- Shake the drink before use.
- Use a measuring cup, measuring spoon or dosing syringe to measure out the correct amount.
- During an epilepsy attack, a family member, caregiver or doctor will administer the nasal spray to you.
- When using the spray for the first time, the pump must be pressed a few times in the air. The spray chamber can then fill with the solution. This is no longer necessary the following times.
- Your head is held upright.
- The nozzle is placed in one nostril and the other nostril is pressed closed.
- The pump is pressed once.
- After use, the spout should be thoroughly cleaned with lukewarm water and the bottle closed tightly.
- During an epilepsy attack, a family member, caregiver or doctor will administer the enema to you.
- You will be placed on your side with your bottom leg straight and your top leg raised.
- The cap is removed.
- The long spout is introduced into the intestine through the anus as far as possible.
- The bottle is slowly squeezed empty.
- The spout is removed from the anus while the bottle is being held down. This will prevent the liquid from flowing back into the bottle.
- You should lie there for five to ten minutes if possible to prevent the liquid from coming out again.
Liquid for the cheek pouch
- During an epilepsy attack, a family member, caregiver or doctor will administer this liquid to you.
- Use an ampoule of solution for injection.
- The correct amount of liquid is drawn from the ampoule using a syringe with a needle.
- The needle is removed from the syringe.
- The liquid is slowly injected into the cheek pouch. The liquid should not come out of the mouth.
- The liquid is rubbed over the mucous membrane of the cheek with fingers.
- Injections are administered by a doctor or nurse.
When? Insomnia Take the medicine about half an hour before going to sleep. Only take it if you have at least seven hours to sleep after taking it. If you have to wake up before then, you will still be too bothered by the narcotic effect. Medical procedures or examinations Your doctor has indicated the time in advance for you to take this medicine. For the tablets, this is often half an hour before the procedure or the examination. An injection works within five minutes. Epilepsy You should use this medicine if the epilepsy attack lasts longer than five minutes. How long? InsomniaIf you use this medicine once in a while, it can help you sleep well. If you use it almost every night, the effect will disappear after a few weeks. Therefore, only use it in special situations. With daily use for a few days, you run the risk of ‘withdrawal insomnia’. Your body expects the effect of this drug to help you fall asleep. Therefore only use it occasionally and never more than a few days in a row. Epilepsy The seizure usually stops when you use this medicine once. Sometimes it is necessary to use this medicine again. If the attack does not stop, you have to go to the hospital. You will be treated further in the hospital. Hiccups Use this medicine for as long as you continue to experience hiccups. What if I miss a dose?Insomnia Are you unable to sleep at night and still want to take a sleeping aid? This is possible, but keep in mind that the sleeping aid will continue to work for several hours. If you have to get up earlier, you will have difficulty waking up and will have a reduced ability to react later. If I am on this medication, can I… drive? It can be dangerous to participate in traffic while taking this medicine. Do you want to know whether you can drive a car with this medicine? Then answer the questions in the diagram below. Note: if you have epilepsy, you are often not allowed to drive. Whether you are allowed to drive depends on certain inspection requirements. Discuss this with your doctor. There is also a brochure‘Epilepsy and fitness to drive’ from the Epilepsy Fund. Would you like more information about driving with certain conditions? Then take a look at the website of the CBR. * Note: Are you taking this medicine as a sleep aid? It only works well if you use it occasionally. The effect decreases with daily use. Your body then gets used to the effect. For more general information you can read the topic ‘Medicines in traffic’. In this theme you can read, for example, what the law says about medicines in traffic. You will also find advice that you should take into account if you are allowed to drive (again). drinking alcohol? Limit the use of alcohol and avoid drinking it. This medicine makes you react much more strongly to alcohol than you are used to. In addition, alcohol increases the side effects of this drug, such as drowsiness and reduced coordination. eat everything? If you drink grapefruit juice or eat grapefruit while taking midazolam, you have an added chance of side effects. Especially if you drink a lot of grapefruit juice or eat grapefruit. The chance of side effects is small:
- if you drink up to 1 glass of grapefruit juice at a time or eat 2 grapefruits at a time;
- if you drink grapefruit juice or eat grapefruit up to twice a week; and
- if you drink grapefruit juice or eat grapefruit with an interval of 3 days or more.
If you experience a lot of side effects, you should contact your doctor or pharmacist. For more information you can find the folder hereto download. Does this medicine interact with other medications? This drug interacts with other drugs. The text below only lists the active ingredients of these drugs, not the brand names. You can find out whether your medicine contains one of these active ingredients in your package leaflet under the heading ‘composition’. The drugs with which the main interactions occur are the following. Other drugs that reduce reaction time. These medicines often have a yellow warning sticker on the packaging. The effects on responsiveness and coordination capacity are mutually reinforcing. Then midazolam can work for longer than 3 days. For example, you will no longer be able to drive a car. The following medications can increase the amount of midazolam in the blood. This makes the effect and side effects, such as drowsiness, stronger. Consult your doctor if you have been prescribed this combination. They may be able to prescribe you a drug that does not interact with this.
- The antidepressants fluoxetine and fluvoxamine.
- The medicines for cardiovascular disease verapamil and diltiazem.
- The antibiotics erythromycin and clarithromycin.
- The anti-fungal medicines itraconazole, ketoconazole, fluconazole, posaconazole and voriconazole.
- The stomach medicine cimetidine.
- Medicines used for HIV infection: atazanavir, darunavir, fosamprenavir, indinavir, lopinavir, ritonavir, saquinavir and tipranavir.
- Telaprevir, simepravir and boceprevir, medicines for hepatitis C.
The following medications reduce the effect of midazolam. Your doctor will need to take this into account when determining the dose. The doctor may be able to prescribe a drug that does not interact with this.
- The epileptic drugs phenytoin, carbamazepine, barbiturates such as phenobarbital, primidone. Some of these drugs are also used for nerve pain or manic depression.
- The tuberculosis drugs rifabutin and rifampin.
- Medicines containing St. John’s wort. This is also called hypericum and is available without a prescription.
- The anti-cancer drugs dabrafenib and enzalutamide.
Not sure if any of the above interactions are of interest to you? Please contact your pharmacist or doctor. Can I use this medicine if I am pregnant, planning to become or breastfeeding? Pregnancy Report it to your doctor and pharmacist as soon as you are pregnant or plan to become pregnant soon. Not enough is known about the use of this medicine during pregnancy to know for sure whether it is safe. Therefore, work with your doctor to weigh the severity of your condition against the risk to the child. DO NOT take this medication from the eighth month of pregnancy. When used after the eighth month, your child may be so dazed and floppy after birth that it has difficulty breathing. In addition, withdrawal symptoms may develop in the baby.
Single use during an epilepsy attack is possible. Discuss this with your doctor. Breast-feeding If you want to breast-feed, talk to your doctor or pharmacist. This drug passes into breast milk. It can then cause side effects in the child. Your doctor may be able to (temporarily) prescribe you another medicine that you can use safely. Can I just stop with this medicine? If you have only used this medicine for a few days in a row, you can stop all at once. In general, withdrawal symptoms do not occur. InsomniaHave you used this sleeping aid for several days in a row, and then you suddenly stop using it? Then you run the risk of ‘withdrawal insomnia’. Your body expects the effect of the sedative to help you fall asleep. This makes sleeping more difficult in the beginning. Therefore only use it occasionally and never more than a few days in a row. Have you used it for a long time? Then gradually reduce the dosage.